Browse our selection of 14 Casino hotels & resorts in San Diego, CA for the ultimate stay & play vacation. Viejas Casino & Resort is the best casino in San Diego with the best players club, myViejas, exciting casino gaming, award-winning dining, and luxurious. . San Diego Casino Hotels · 1. Make your casino vacation a sure bet with Expedia. The design is contemporary and. Holiday Inn Express San Diego N - Rancho Bernardo. Get your playcation on with world-class gaming in the largest non-smoking gaming floor in California with iconic local eateries, pool, spa and so much more! Top San Diego County Casino Resorts & Hotels · Viejas Casino & Willows Hotel · Harrah's Resort Southern California · Ayres Lodge Alpine · Singing Hills Golf Resort. Encircled by rolling green hills, the resort overlooks a 1,acre reservation, home of the Viejas Band of the Kumeyaay Indians. Viejas Casino & Willows Hotel · Harrah's Resort Southern California · Ayres Lodge Alpine · Singing Hills Golf Resort · Pala Casino Spa And Resort · Rainbow Inn Bed. Spacious deluxe rooms, luxurious amenities with natural backdrops & golf. TownePlace Suites San Diego Central · 2. Valley View Casino & Hotel offers beautiful rooms and endless entertainment. Explore our casino resort in San Diego & relax in one of our hotel rooms! Experience a relaxing retreat at Southern California's Barona Resort & Casino.